Microsoft has officially launched the App-V 4.6 beta program.
This version is still oriented to client applications but introduces a major new feature: the support for 64bit platforms (including the just released Windows 7 and Windows Server 2008 R2).
For the first time customers will be able to sequence a 64bit application, something that nobody else on the market can do at the moment according to Microsoft.
Microsoft expects to finalize App-V 4.6 during H1 2010. Meanwhile you can enroll for the beta program here